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- USA
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Ships within 48 hours · Estimated delivery Jul 8 - Jul 13
For Your Every Summer RSVP, with Code: SUMMER15
Description
CK-4 Recombinant Rabbit mAb(SDT-046-12)Product Specification Host Rabbit Antigen CK 4 Synonyms Keratin 4 (K4); Type II keratin Kb4 Immunogen Synthetic Peptide Accession P19013 Clone Number SDT 046 12 Antibody Type Rabbit mAb Application WB, IHC P, ICC Reactivity Hu, Ms Purification Protein A Concentration 0. 5mg ml Molecular Weight 56kDa Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months from
Product Specification
| Host | Rabbit |
| Antigen | CK-4 |
| Synonyms | Keratin-4 (K4); Type-II keratin Kb4 |
| Immunogen | Synthetic Peptide |
| Accession | P19013 |
| Clone Number | SDT-046-12 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms |
| Purification | Protein A |
| Concentration | 0.5mg/ml |
| Molecular Weight | 56kDa |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| ICC | 1:500 | |
| IHC-P | 1:1000-1:2000 | |
| WB | 1:1000 |
Background
Keratin 4 is a type II cytokeratin. It is specifically found in differentiated layers of the mucosal and esophageal epithelia together with keratin 13. Mutations in the genes encoding this protein have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia.Keratin 4 partners with a similar protein, keratin 13 (produced from the KRT13 gene), to form molecules known as intermediate filaments. These filaments assemble into strong networks that provide strength and resilience to the different mucosae. Networks of intermediate filaments protect the mucosae from being damaged by friction or other everyday physical stresses.
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